Today during clinical medicine session we had a case of HHT (Hereditary Hemorrhagic Telangiectasia). A female, single (unmarried) patient of 46 years old from Mosul presented with Epistaxis (nosebleeds), Hematemesis (vomiting of blood), Melena (black stool) and anemia. She had been suffering from this condition for three years with a family history of the same condition. HHT is a hereditary condition transmitted in an autosomal dominant fashion, and occurs in one in 5,000 people. It is also called Osler-Weber-Rendu syndrome that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver and brain. Treatment focuses on reducing bleeding from blood vessel lesions, and sometimes surgery or other targeted interventions to remove arteriovenous malformations in organs.